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Antimicrobial and Free Radical Scavenging Activities of Cellulose/Silver-Nanocomposites with In Situ Generated Silver Nanoparticles Using Cissampelos Pareira Leaf Extract

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Abstract

In this study, silver nanoparticles (AgNPs) were in situ generated on the surface of cellulose matrix using leaf extract of cissampelos pareira (LCP) by environmentally benign green synthesis. The morphological and structural properties of synthesized cellulose silver nanocomposites (Cel/LCP/Ag-NCs) were characterized by different spectral studies such as UV–visible spectroscopy, SEM, TEM, FT-IR, AFM, DRS, PL, Lifetime, XPS and XRD. Silver nanoparticles were obtained in the cellulose matrix with an average size of 34.26 nm and with antioxidant activity which has been evaluated by ABTS (70.34% at 100 µg/mL) and DPPH (81.65% at 100 µg/mL) methods. The antimicrobial properties of cellulose, Cel/LCP, Cel/LCP (10 mM, 30 mM and 50 mM AgNO3), tested on 13 microorganisms were determined using disk diffusion method. The most effective nanocomposites (Cel/LCP/10, 30 and 50 mM AgNO3), Cel/LCP/50 mM AgNO3 afforded the best antimicrobial properties because increasing the concentration of AgNO3 solution, the zone of inhibition also increased. The prepared cellulose silver nanocomposites synthesized by leaf extract of cissampelos pareira shows the potential to be applied in the future development of therapeutics and biomedical applications.

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Authors and Affiliations

  1. PG and Research Department of Chemistry, Sri Vijay Vidyalaya College of Arts and Science, Dharmapuri, Tamilnadu, 636807, India

    Chinnadurai Shanmugam & Poongavanam Govindhan

  2. Department of Sciences, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Coimbatore, Tamilnadu, 641112, India

    Ganarajan Sivasubramanian

  3. Surface Engineering Division, CSIR, National Aerospace Laboratories, Bangalore, 560017, India

    Parthasarathi Bera

  4. Department of Biochemistry, Sree Narayana Guru College, Coimbatore, Tamilnadu, 641105, India

    Krishnan Baskaran

  5. Department of Chemistry, Annamalai University, Annamalainagar, Tamilnadu, 608002, India

    Veembil Ramachandra Iyer Parameswaran

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  1. Chinnadurai Shanmugam
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  2. Ganarajan Sivasubramanian
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  4. Parthasarathi Bera
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Correspondence to Chinnadurai Shanmugam.

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Shanmugam, C., Sivasubramanian, G., Govindhan, P. et al. Antimicrobial and Free Radical Scavenging Activities of Cellulose/Silver-Nanocomposites with In Situ Generated Silver Nanoparticles Using Cissampelos Pareira Leaf Extract. J Clust Sci 33, 1727–1737 (2022). https://doi.org/10.1007/s10876-021-02097-2

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  • DOI: https://doi.org/10.1007/s10876-021-02097-2

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