Abstract
Nematodes of the Ancylostomidae family consist of important parasitic species. The control of such parasitosis represents an important challenge, given the constant high rate of reinfection of some hosts, among which the domestic dog, as well as the high environmental contamination. Another factor that can have a negative influence is the toxicity of the chemicals used for environmental decontamination, highlighting the need to design research to identify new control strategies for this parasitosis, among which the use of plant extracts. Thus, the objective of this research was to evaluate the toxicity and ovicidal activity of hydroalcoholic extracts obtained by percolation of three plants: Tagetes minuta L., Euphorbia milli var splendens (Bojer ex Hook.) Ursch & Leandri and Synadenium carinatum Boiss, against Ancylostoma spp. In addition, these extracts were tested at different concentrations for toxicity against Artemia salina L. and Allium cepa L. It was observed that the hydroalcoholic extract of all plant species evaluated induced moderate ovicide activity at all the tested concentration, with emphasis on E. milii, which was the only plant species that presented significantly low toxicity in the concentration of 12.5 µL/mL when compared to the other species evaluated.
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We thank UniFUNVIC for the opportunity to outline the experiments in the laboratories involved.
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Coêlho, M.D.G., Maciel, L.T.R., de Fátima Kieko Ozaki, T. et al. Ovicidal and toxicological effect of hydroalcoholic extracts of Euphorbia milli var splendens, Synadenium carinatum Boiss and Tagetes minuta L. against Ancylostoma spp.: In vitro study. J Parasit Dis 45, 252–257 (2021). https://doi.org/10.1007/s12639-020-01302-9
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DOI: https://doi.org/10.1007/s12639-020-01302-9