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2009, Rec Nat Prod
Abstract: From the whole plant of Klainedoxa gabonenses betulinic acid (1), lupeol (2), ß-sitosterol (3), βamyran-3-one (4) and 3, 3', 4'-tri-O-methylellagic acid (5) were isolated. Similarly paullinomide A (6), β-amyrin (7), 2-(4-hydroxy-3, 5-dimethoxyphenyl)-3-hydroxymethyl-2, 3-dihydro-1, 4, 5-trioxaphenanthren-6-one (8), 5αporiferastane-3ß, 6α-diol (9), β-sitosterol (3), l-quebrachitol (10), and ß-sitosterol glucopyranoside (11) were isolated from roots of Paullinia pinnata. Preliminary studies showed that 2-(4-hydroxy-3, 5- ...
Journal of Pharmacognosy and Phytotherapy
Phytochemical analysis of the methanol leaves extract of Paullinia pinnata linn2014 •
International Journal of Phytomedicine
The Medicinal Properties of Paullinia pinnata Linn. Leaves2020 •
Paullinia pinnata is a plant introduced to tropical Africa and has been reported to be useful in folkloric medicine. Different medicinal potentials of the leaves have been investigated some of which have corroborated reports in traditional medicine. Compounds have been isolated from extracts of the leaves which have been shown to have medicinal value. These compounds are from different classes of secondary metabolites including tannins, flavonoids and alkaloids. Fatty acids have also been shown to be present. This report is set to enumerate the traditional use of the leaves of P. pinnata and research findings already documented.
2014 •
Paullinia pinnata Linn (Sapindaceae) is a medicinal plant, locally used in the West Region of Cameroon for the treatment of typhoid fever. This work was designed to evaluate the antityphoid and antioxidant activities of the extracts and compounds of P. pinnata. The methanol extracts of the leaves and stems were tested for antityphoid and antioxidant activities. Compounds were isolated, and their structures elucidated by analysis of spectroscopic data in conjuction with literature data and tested for the same activities. The leaf extract was also tested in vivo for its antityphoid potential in a Salmonella typhimurium-induced typhoid fever model in Wistar rats. Seven known compounds: methylinositol (1), β-sitosterol (2), friedelin (3), 3β-(β-D-Glucopyranosyloxy)stigmast-5-ene (4), (3β)-3-O-(2'-Acetamido-2'-deoxy-β-D-glucopyranosyl) oleanolic acid (5), (3β,16α-hydroxy)-3-O-(2'-Acetamido-2'-deoxy-β-D-glucopyranosyl) echinocystic acid (6) and (3β,)-3-O-[β-D-glucopyranosy...
Avicenna Journal of Medical Biochemistry
Cytotoxic, Antibacterial, and Leishmanicidal Activities of Paullinia pinnata (Linn.) Leaves2021 •
Background Plants are now being explored for use in the treatment and management of clinical diseases (1-4). Paullinia pinnata is a woody or sub-woody climber of the family Sapindaceae. It originates from tropical America and is now common in the savanna zones of tropical Africa and Madagascar (5). The common names are "bread and cheese plant" and "sweet gum" (5,6). Phytochemical screening of the leaves has shown the presence of cardiac glycosides, saponins, alkaloids, anthraquinones, flavonoids, and tannins (6-10). These secondary metabolites have been proposed and shown to be responsible for the observed effects in various investigations where the leaves of P. pinnata have shown antimalarial (11, 12), antioxidant (12-15), antidiarrhoeal (16), hematological (17), anti-typhoid (18), wound healing (19,20), phytotoxic (21), analgesic, and anti-inflammatory activities (8,22,23). These investigations have served to support or validate some of the traditional applications of different preparations of the leaf of P. pinnata in the treatment and management of diverse diseases and ailments. However, its application in the amelioration of other health challenges still needs to be explored. In the light of this, the aim of this study was to investigate the antileishmanial, antibacterial, and cytotoxic effects of P. pinnata leaves using various in-vitro bioassays, which may possibly lead to further investigations. The results of this study would further contribute to the existing knowledge on P. pinnata and provide observations which can be further explored. Materials and Methods Sample Collection and Extraction Fresh leaves of P. pinnata were collected from the Forestry Research Institute of Nigeria (FRIN), Ibadan, Nigeria. They were authenticated and given the specimen voucher number FHI 106555 at the same institute. The leaves were shade-dried at room temperature and the dried leaves were milled and extracted using absolute methanol for 6 hours in a Soxhlet extractor. The extract was concentrated with a rotary evaporator (Heidolph HB, Germany) and a vacuum oven (Gallenhamp, England) at a temperature of 40 o C. A 14% yield of the extract was realized that was stored refrigerated. In Vitro Assays Brine Shrimp Toxicity Assay The modified method of Kivçak et al (24) was employed. First, 20 mg of P. pinnata was dissolved in 2 mL of
Nigerian Journal of Natural Products and Medicine
Phytotoxic activity of the methanol leaves extract of Paullinia pinnata (Linn.)2017 •
There is the need for weed management and control through allelopathy since the use of synthetic herbicides affects and is hindered by various factors which include herbicide-resistant weed populations, deleterious effects on non-target as well as soil and water pollution. Paullinia pinnata leaves are employed traditionally for the treatment of various ailments and as fish poison, and may also have herbicidal effects. To investigate this, possible phytotoxic property of the leaves of P. pinnata was explored and this is the aim of this study. The activity of the extract against the growth of Lemna minor was used to investigate the phytotoxic activity. The activity of the methanol extract of P. pinnata leaves against Lemna minor increased in a dose- dependent manner and was significant at 1000 μg/ml. Therefore, the methanol leaves extract of P. pinnata exhibited significant phytotoxic activity. Keywords: Paullinia pinnata , Lemna minor , phytotoxicity
Natural Product Research
Antibacterial and antifungal activities of acetonic extract from Paullinia cupana Mart. seeds2013 •
The Journal of pharmacy and pharmacology
Two novel lupane triterpenoids from Paullinia pinnata L. with fibroblast stimulatory activity2010 •
Novel lupane triterpenoids from Paullinia pinnata L., a Ghanaian plant traditionally used for wound healing, were examined for in-vitro fibroblast stimulatory activity using the 142BR cell line. Bioactivity-guided isolation of the crude extract of P. pinnata L. was carried out in order to determine the nature of the compounds responsible for the stimulation of fibroblast proliferation. Two novel compounds were isolated and characterised, namely, 6beta-(3'-methoxy-4'-hydroxybenzoyl)-lup-20(29)-ene-one (1) and 6beta-(3'-methoxy-4'-hydroxybenzoyl)-lup-20(29)-ene-ol (2), together with three known compounds, friedelin (3), beta-sitosterol (4) and beta-sitosterol-3-D-glucoside (5). The methanol extract of the roots of P. pinnata caused a significant in-vitro increase (94%) in 142BR cell line proliferation at 20 microg/ml compared with the control. Compounds 1 and 2, which were isolated from the active chloroform fraction, have not previously been reported and showed a dose...
Nigerian Journal of Natural Products and Medicine
Phytotoxic activity of the methanol leaves extract of Paullinia pinnata (Linn.)2016 •
There is the need for weed management and control through allelopathy since the use of synthetic herbicides affects and is hindered by various factors which include herbicide-resistant weed populations, deleterious effects on non-target as well as soil and water pollution. Paullinia pinnata leaves are employed traditionally for the treatment of various ailments and as fish poison, and may also have herbicidal effects. To investigate this, possible phytotoxic property of the leaves of P. pinnata was explored and this is the aim of this study. The activity of the extract against the growth of Lemna minor was used to investigate the phytotoxic activity. The activity of the methanol extract of P. pinnata leaves against Lemna minor increased in a dose- dependent manner and was significant at 1000 µg/ml. Therefore, the methanol leaves extract of P. pinnata exhibited significant phytotoxic activity. Keywords: Paullinia pinnata, Lemna minor, phytotoxicity
Journal of Saudi Chemical Society
New triterpene isovanniloyl and antibacterial activity of constituents from the roots of Paullinia pinnata Linn (Sapindaceae)2012 •
African Journal of …
Volatile compounds of maari, a fermented product from baobab (Adansonia digitata L.) seeds2011 •
Evidence Based Mental Health
Advances in our understanding of the genetics of childhood neurodevelopmental disordersEuropäisches Journal für Minderheitenfragen
“Last among equals”: Irish Travellers and change in the 21st century2012 •
Edu Cendikia: Jurnal Ilmiah Kependidikan
Keterampilan Menulis Puisi dengan Media Gambar Tokoh Pahlawan di Kelas IV SDMarmara Üniversitesi İlahiyat Fakültesi Dergisi
el-Câmi‘u’s-sahîh’in “Eyyâmü’l-Câhiliye” Babı Çerçevesinde Buhârî’ye Göre Câhiliye Kavramı / Ayşe Esra ŞAHYAR2016 •
Journal of Orthopaedic Surgery and Research
Retraction Note: Clinical efficacy of posterior versus anterior instrumentation for the treatment of spinal tuberculosis in adults: a meta-analysis2015 •
Pharmacology Biochemistry and Behavior
The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes2005 •
Interdisciplinary Research in Counseling, Ethics and Philosophy - IRCEP
The garden is the new café: Vegetal metaphysics and community philosophyJournal of Crystal Growth
On the growth of small crystals of Cd, Zn, Pt and Rh during electron microscope observations1987 •
International Journal of Criminal, Common and Statutory Law
Judicial organization and institutions in Cameroon: A tripartite classification2024 •
Proceedings of the National Academy of Sciences
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri2006 •
International Journal of Advanced Research
Management Of C- Shaped Canal A Case Report2016 •
2012 •