Antimicrobial Activity of the Essential Oil and Some Isolated Sulfur-Rich Compounds from Scorodophloeus zenkeri

 

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Abstract

The essential oil and several pure sulfur compounds isolated from Scorodophloeus zenkeri were tested for their antibacterial and antifungal activity using a paper disc method, the poisoned food technique, a microatmosphere method and the measurement of cellular ATP content. The essential oil completely inhibited the growth of all fungi tested including yeasts, with the exception of Aspergillus flavus, and was active against the Gram-positive bacteria studied, but not the Gram-negative organisms. 2,4,5,7-Tetrathiaoctane, 2,4,5,6,8-pentathianonane, 2,3,4,6,8-pentathianonane, 2,3,5,6,8,10-hexathiaundecane, 2,3,5-trithiahexane 5-oxide, 2,4,5,7-tetrathiaoctane 2-oxide, 2,3,5,7-tetrathiaoctane 3,3-dioxide and 2,3,5-trithiahexane 3,3-dioxide differed in their effects on the strains studied with respect to both growth and synthesis of cellular ATP. 2,3,5-Trithiahexane, 2,3,4,6-tetrathiaheptane, methyl methanethiosulfonate and bis-methyl-sulfonylmethane exhibited no antimicrobial activity.

References

• 1 Chen I S, Chen H F, Cheng M J, Chang Y L, Teng C M, Tsutomu I. et al . Quinoline alkaloids and other constituents of Melicope semecarpifolia with antiplatelet aggregation activity.  Journal of Natural Products. 2001;  64 1143-7
  CrossrefPubMedGoogle Scholar
• 2 Vairappan C S, Suzuki M, Abe T, Masuda M. Halogenated metabolites with antibacterial activity from the Okinawan Laurencia species.  Phytochemistry. 2001;  58 517-23
  CrossrefPubMedGoogle Scholar
• 3 Resch M, Heilmann J, Steigel A, Bauer R. Further phenols and polyacetylenes from the rhizomes of Atractylodes lancea and their anti-inflammatory activity.  Planta Medica. 2001;  67 437-42
  Article in Thieme ConnectPubMedGoogle Scholar
• 4 Aubréville A, Leroy J F. Flore du Cameroun. 9 Légumineuses-Césalpinioidées. Muséum National d’Histoire Naturelle, Laboratoire de Phanérogamie 1970: P. 83-6
  Google Scholar
• 5 Amvam Zollo P H, Dupont Youngo M J, Fekam B F, Menut C, Lamaty G, Bessière J M. Etude comparée de la composition chimique des huiles essentielles extraites à partir d’un ”arbre à ail”: Scorodophloeus zenkeri Harms (Caesalpiniacee) et de l’ail: Allium sativum Linn. (liliacee) du Cameroun. Actes des 14èmes Journées Internationales Huiles Essentielles, Digne-les-Bains 1995: 614-7
  Google Scholar
• 6 Hegnauer R, Hegnauer M. Chemotaxonomie der Pflanzen XIb-1 Leguminosae Teil 2. Birkhäuser Verlag Basel, Boston, Berlin; 1996: P. 152
  Google Scholar
• 7 Kouokam J C, Zapp J, Becker H. Isolation of new alkylthiosulfides from the essential oil and extracts from the bark of Scorodophloeus zenkeri Harms.  Zeitschrift für Naturforschung. 2001;  56c 1003-7
  PubMedGoogle Scholar
• 8 Kouokam J C, Zapp J, Becker H. Oxygen-containing sulfur-rich compounds from the bark of the tropical garlic tree Scorodophloeus zenkeri Harms.  Phytochemistry. 2002;  60 403-7
  CrossrefPubMedGoogle Scholar
• 9 Dannhardt G, Grobe A, Gußmann S. 5-(3-Aminopropyl)-isoxazole: Synthese und antibakterielle Aktivität einiger Derivate.  Archiv der Pharmazie. 1988;  321 163-6
  PubMedGoogle Scholar
• 10 Ioset J R, Marston A, Gupta M P, Hostettmann K. Antifungal and larvicidal meroterpenoid naphthoquinones and a naphthoxirene from the roots of Cordia linnaei .  Phytochemistry. 1998;  47 729-34
  CrossrefPubMedGoogle Scholar
• 11 Grover R K, Moore J D. Toximetric studies of fungicides against the brown rot organisms, Sclerotinia fructicola and S. laxa .  Phytopathology. 1962;  52 876-80
  PubMedGoogle Scholar
• 12 Mishra A K, Dubey N K. Evaluation of some essential oils for their toxicity against fungi causing deterioration of stored food commodities.  Applied and Environmental Microbiology. 1994;  60 (4) 1101-5
  PubMedGoogle Scholar
• 13 Jahns T. Ammonium/urea-dependent generation of a proton electrochemical potential and synthesis of ATP in Bacillus pasteurii .  Journal of Bacteriology. 1996;  178 (2) 403-9
  PubMedGoogle Scholar
• 14 Benjilali B, Tantaoui-Elakari A, Ayadi A, Ihlal M. Method to study antimicrobial effects of essential oils: application to the antifungal activity of six Moroccan essences.  Journal of Food Protection. 1984;  47 748-52
  PubMedGoogle Scholar
• 15 Naigre R, Kalck P, Roques C, Roux I, Michel G. Comparison of antimicrobial properties of monoterpenes and their carbonylated products.  Planta Medica. 1996;  62 275-7
  PubMedGoogle Scholar
• 16 Lim H, Kubota K, Kobayashi A, Seki T, Ariga T. Inhibitory effect of sulfur containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets.  Bioscience, Biotechnology and Biochemistry. 1999;  63 (2) 298-301
  CrossrefPubMedGoogle Scholar
• 17 Kubota K, Ohhira S, Kobayashi A. Identification and antimicrobial activity of the volatile flavor constituents from Scorodocarpus borneensis Becc.  Journal of Bioscience, Biotechnology and Biochemistry. 1994;  52 (4) 644-6
  PubMedGoogle Scholar

Dr. Thomas Jahns

FR 8.3, Mikrobiologie, Universität des Saarlandes

66041 Saarbrücken

Germany

Email: toja@rz.uni-sb.de

Phone: +49 681 302 2225

Fax: +49 681 302 3986